Details for gene set NCI_IL23-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_DMproB_versus_LMproB.phenotype_DMproB_versus_LMproB.cls #DMproB_versus_LMproB
Phenotype	phenotype_DMproB_versus_LMproB.cls#DMproB_versus_LMproB
Upregulated in class	DMproB
GeneSet	NCI_IL23-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	0.7634265
Normalized Enrichment Score (NES)	1.843077
Nominal p-value	0.0
FDR q-value	8.534279E-4
FWER p-Value	0.0010

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RELB	17942	179	2.396	0.0627	Yes
2	SOCS3	20131	241	2.127	0.1236	Yes
3	IL1B	14431	253	2.069	0.1854	Yes
4	STAT3	5525 9906	266	2.009	0.2454	Yes
5	BCL3	8654	305	1.927	0.3015	Yes
6	NFKB2	23810	341	1.794	0.3537	Yes
7	ARRB2	20806	357	1.753	0.4058	Yes
8	CYLD	18532	405	1.659	0.4534	Yes
9	BCL10	15397	471	1.553	0.4967	Yes
10	STAT5A	20664	502	1.497	0.5403	Yes
11	MAPK14	23313	503	1.495	0.5854	Yes
12	STAT4	14251 9907	557	1.405	0.6250	Yes
13	MAP3K14	11998	807	1.093	0.6445	Yes
14	RAN	5356 9691	933	1.000	0.6680	Yes
15	TNFAIP3	19810	1333	0.722	0.6683	Yes
16	BIRC2	4397 4398	1334	0.722	0.6900	Yes
17	CHUK	23665	1368	0.706	0.7096	Yes
18	TYK2	12058 19215	1482	0.637	0.7227	Yes
19	IKBKB	4907	1513	0.621	0.7398	Yes
20	NFKB1	15160	1638	0.564	0.7501	Yes
21	NFKBIA	21065	1694	0.538	0.7634	Yes
22	NOD2	6384	2275	0.332	0.7422	No
23	MALT1	6274	2732	0.225	0.7244	No
24	IL12RB1	3916 18582	2889	0.201	0.7220	No
25	CXCL9	5099	3370	0.144	0.7005	No
26	SYK	21636	3556	0.125	0.6943	No
27	XPO1	4172	3925	0.101	0.6775	No
28	TNF	23004	4343	0.080	0.6575	No
29	TNFRSF1A	1181 10206	4442	0.076	0.6545	No
30	IL18RAP	14262	4611	0.070	0.6475	No
31	IL23A	19598	4729	0.066	0.6432	No
32	FBXW11	20926	4860	0.062	0.6381	No
33	IL23R	17127	5720	0.042	0.5930	No
34	ITGA3	20284	5970	0.038	0.5807	No
35	ERC1	1013 17021 995 1136	6634	0.027	0.5458	No
36	IL19	13839	6719	0.026	0.5421	No
37	ALOX12B	20825	6889	0.024	0.5337	No
38	PIK3R1	3170	7282	0.019	0.5131	No
39	ATM	2976 19115	7356	0.018	0.5097	No
40	CXCL1	9044	7802	0.013	0.4861	No
41	UBE2D3	7253	8041	0.010	0.4736	No
42	PIK3CA	9562	8241	0.008	0.4631	No
43	CD3E	8714	8370	0.006	0.4564	No
44	CCL2	9788	8529	0.004	0.4480	No
45	IL6	16895	8787	0.002	0.4342	No
46	IL2	15354	9362	-0.004	0.4034	No
47	IL12B	20918	9683	-0.007	0.3863	No
48	IL17F	13992	10139	-0.011	0.3622	No
49	IL24	976 13841	10347	-0.013	0.3514	No
50	RIPK2	2528 15935	10837	-0.019	0.3256	No
51	JAK2	23893 9197 3706	11684	-0.030	0.2809	No
52	IKBKG	2570 2562 4908	12271	-0.038	0.2505	No
53	SRC	5507	12732	-0.046	0.2271	No
54	IL18R1	14263	13154	-0.054	0.2060	No
55	LCK	15746	13709	-0.070	0.1783	No
56	IFNG	19869	14286	-0.093	0.1500	No
57	CD4	16999	14357	-0.096	0.1491	No
58	IL18	9172	14486	-0.103	0.1453	No
59	IL17A	14289	15316	-0.165	0.1056	No
60	REL	9716	15371	-0.171	0.1079	No
61	RELA	23783	16057	-0.286	0.0796	No
62	TRAF6	5797 14940	16432	-0.382	0.0710	No
63	PRKCA	20174	16682	-0.460	0.0714	No
64	STAT1	3936 5524	16743	-0.486	0.0828	No
65	MPO	5116 20710 1324	17023	-0.599	0.0859	No